… VAR2CSA comprises an intracytoplasmic region, a … a similar pattern of activity as naturally
acquired antibody needs to … to epitopes from different variants of VAR2CSA. Investigations are …

… between study sites likely represent different sample types and sample storage. Among the
available … The NTS-DBL2X region of VAR2CSA induces cross-reactive antibodies that inhibit …

… sera showed antibody binding to peptides P23–P25 and one sample also … of antibodies
capable of binding to the VAR2CSA variants. … the region NTS-DBL2X can bind to antibodies from …

… of the pattern seen for BIA against the parasite variants (see … might be related to the differential
display of antigens on the IE … to identify VAR2CSA epitopes shared by multiple variants of …

… naturally acquired antibodies; these patterns differ between … that these atypical migration
patterns could arise from incorrect … the differential binding affinity of various alleles of VAR2CSA …

… antibodies with specificity for the PAMVAC region of genetic variants representing different
clades of VAR2CSA … vaccinated volunteers with a pattern that represented genetic distance (ie…

… region of VAR2CSA are able to induce cross-inhibitory … the antibody cross-reactivity against
different VAR2CSA variants … or rational structure-based designs. Finally, the recently hyped …

… Areas covered: This review analyzes the progress made thus far in … that antibodies raised
against two (FCR3 and 3D7) VAR2CSA variants of NTS-DBL2X exhibited different patterns of …

… var2CSA can be inhibited by incubation with DBL2X, DBL3X or DBL5ε domains. The Nterminal
NTS-DBL2X region of … ICAM-1 and is a target of cross-reactive, adhesion-inhibitory anti- …

… discussed variation of the var2csa gene. The variable … suggested that antibodies raised
against VAR2CSA are not cross… We suggest to base sample size calculation on a clinical primary …